Masoprocol

Masoprocol

Clinical data
Trade names	Actinex
AHFS/Drugs.com	Micromedex Detailed Consumer Information
Routes of administration	Topical
ATC code	L01XX10 (WHO)
Pharmacokinetic data
Bioavailability	Very low
Identifiers
IUPAC name 4-[(2R,3S)-4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol
CAS Number	27686-84-6 Y
PubChem CID	71398
IUPHAR/BPS	4265
DrugBank	DB00179 Y
ChemSpider	64490 Y
UNII	7BO8G1BYQU
ChEBI	CHEBI:73468 N
ChEMBL	ChEMBL313972 N
CompTox Dashboard (EPA)	DTXSID5045178
ECHA InfoCard	100.044.172
Chemical and physical data
Formula	C18H22O4
Molar mass	302.370 g·mol−1
3D model (JSmol)	Interactive image
SMILES Oc1ccc(cc1O)C[C@H](C)[C@H](C)Cc2ccc(O)c(O)c2
InChI InChI=1S/C18H22O4/c1-11(7-13-3-5-15(19)17(21)9-13)12(2)8-14-4-6-16(20)18(22)10-14/h3-6,9-12,19-22H,7-8H2,1-2H3/t11-,12+ Y Key:HCZKYJDFEPMADG-TXEJJXNPSA-N Y
NY (what is this?)  (verify)

Masoprocol is an antineoplastic drug used to treat skin growths caused by sun exposure. It is the meso form of nordihydroguaiaretic acid that is taken by mouth. The substance is being studied in the treatment of prostate cancer.

Masoprocol is also called NDGA, and Actinex.

Nordihydroguaiaretic acid is an antioxidant, and it may block certain enzymes needed for tumor growth.

It is a lipoxygenase inhibitor.^[1]

• MedlinePlus Drug Information
• Actinex entry in the public domain NCI Cancer Dictionary

This antineoplastic or immunomodulatory drug article is a stub. You can help Wik.ipedia.Pro by expanding it.

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